Saturday, October 16, 2021
ADVT 
National

Providence's mRNA vaccine to be made in Winnipeg

Darpan News Desk The Canadian Press, 14 Sep, 2021 04:31 PM
  • Providence's mRNA vaccine to be made in Winnipeg

Calgary-based Providence Therapeutics says it has signed two contracts to have its developmental mRNA vaccine for COVID-19 manufactured in Canada.

The company says it has signed a $90-million, five-year contract with Emergent Biosolutions to make part of the drug substance, and also to fill and finish the vaccine, at its Winnipeg manufacturing plant.

Another $15-million contract was signed with Calgary's Northern RNA firm to make some of the raw materials needed to produce the messenger RNA in the vaccine.

Providence this week reported that a Phase 1 trial, involving 60 adults between 18 and 64, showed its mRNA vaccine is producing immunity levels comparable to those produced by authorized mRNA vaccines from Pfizer-BioNTech and Moderna.

A Phase 2 clinical trial in 525 people is now about to begin to further test the safety and effectiveness of the vaccine.

Canada has yet to authorize a made-in-Canada vaccine for COVID-19 and has relied mostly on importing mRNA vaccines from Pfizer and Moderna.

As of Tuesday, 26 million Canadians have been fully vaccinated against COVID-19, and another 2.4 million people have received their first dose.

Canada's lacklustre manufacturing capacity for vaccines was a major issue heading into the COVID-19 vaccination procurement process and the federal government is working to expand the industry.

The vaccines from Moderna and Pfizer are the first mRNA products authorized for widespread use and have been critical to helping slow the COVID-19 pandemic in Canada and elsewhere.

The technology is being researched for use on a number of other conditions including cancers and influenza.

Moderna recently signed an agreement to build a manufacturing plant for its mRNA vaccine somewhere in Canada, but the location has yet to be chosen. Earlier this week Moderna announced it has also signed a contract with National Resilience for the latter to start producing the mRNA used in Moderna's vaccine.

The federal government last spring invested almost $200 million to help Resilience expand its manufacturing facility in Mississauga, Ont., so it can make more vaccines, including mRNA vaccines.

Emergent BioSolutions is based in Maryland and has multiple facilities in the U.S., Canada and Europe. The company was heavily criticized earlier this year when a mistake in manufacturing at one site in Baltimore, Md., led to the destruction of at least 60 million doses of Johnson & Johnson's COVID-19 vaccine.

 

MORE National ARTICLES

Warmer-than-normal fall expected this year

Warmer-than-normal fall expected this year

The network says in its fall forecast that much of Canada can expect some spells of warm temperatures in the next month or so, mixed in with the wide swings in weather the season typically brings.

Warmer-than-normal fall expected this year

Trudeau, O'Toole tied as campaign hits final bend

Trudeau, O'Toole tied as campaign hits final bend

The poll conducted by Leger in collaboration with The Canadian Press indicates the parties are tied with the support of 32 per cent of decided voters, with the NDP in third place with 20 per cent.

 

 

Trudeau, O'Toole tied as campaign hits final bend

Tens of thousands have 'long COVID-19' symptoms

Tens of thousands have 'long COVID-19' symptoms

In a brief released today, the Ontario COVID-19 Science Advisory Table says the symptoms of so-called long COVID can last from weeks to months after contracting the virus.

 

 

Tens of thousands have 'long COVID-19' symptoms

Suspect allegedly involved in two shootings in Richmond in-custody

Suspect allegedly involved in two shootings in Richmond in-custody

There are no concerns for public safety at this time. The motive for these shootings and whether there is a nexus to the Lowermainland gang conflict are still under investigation.

Suspect allegedly involved in two shootings in Richmond in-custody

Health workers in B.C. must get COVID-19 vaccine

Health workers in B.C. must get COVID-19 vaccine

Dr.Henry says about 15,000 British Columbians who are severely immunocompromised will receive a third dose in accordance with guidance from the National Advisory Committee on Immunization. They include those who've received an organ, bone marrow or stem cell transplant.

Health workers in B.C. must get COVID-19 vaccine

1,984 COVID19 cases over 3 days

1,984 COVID19 cases over 3 days

 85.8% (3,978,624) of eligible people 12 and older in B.C. have received their first dose of COVID-19 vaccine and 78.4% (3,632,547) received their second dose.

1,984 COVID19 cases over 3 days